翻訳と辞書 Words near each other ・ Eukaryotic chromosome fine structure ・ Eukaryotic chromosome structure ・ Eukaryotic DNA replication ・ Eukaryotic elongation factors ・ Eukaryotic initiation factor ・ Eukaryotic initiation factor 4G ・ Eukaryotic large ribosomal subunit (60S) ・ Eukaryotic Linear Motif resource ・ Eukaryotic Pathogen Database Resources Centre ・ Eukaryotic Promoter Database ・ Eukaryotic release factors ・ Eukaryotic ribosome (80S) ・ Eukaryotic small ribosomal subunit (40S) ・ Eukaryotic transcription ・ Eukaryotic translation ・ Eukaryotic translation elongation factor 1 alpha 1 ・ Eukaryotic translation initiation factor 4 gamma ・ Eukaryotic translation initiation factor 4E family ・ Eukelade ・ Eukey ・ Eukiefferiella ・ Eukrohniidae ・ EUL ・ Eul-Yong Ta ・ Eula ・ Eula (given name) ・ Eula (river) ・ Eula Beal ・ Eula Bingham ・ Eula Biss Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Eukaryotic translation elongation factor 1 alpha 1 ： ウィキペディア英語版 Eukaryotic translation elongation factor 1 alpha 1 Elongation factor 1-alpha 1 (eEF1a1) is a protein that in humans is encoded by the ''EEF1A1'' gene. This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty's syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1915 )〕 ==Structure== Mammalian eEF1A possesses two isoforms, eEF1A1 and eEF1A2, with high amino acid sequence homology (approximately 90% identity). The sequences of their promoter regions are also highly similar, though that of the ''eEF1A2'' gene contains an additional 81 bp SV40 small antigen sequence at the 5′-end. The ''EEF1A1'' 5' UTR also contains a terminal oligopyrimidine tract. Thus, these two isoforms demonstrate differences in expression and function: eEF1A1 is expressed in most cells while eEF1A2 is only expressed in adult neuronal and muscle cells, and only eEF1A1 induces HSP70 during heat shock.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Eukaryotic translation elongation factor 1 alpha 1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.